ANALISIS UKURAN PORI BIOKOMPOSIT [SERICIN-BIOPLASTIK] PADA BERBAGAI PEMBEKUAN DENGAN METODE TAGUCHI

Abstract

Increased demand for medical materials, triggering research into alternative
medical materials. Alternative materials should have the same characteristics for the patient's body. Sericin is a protein that has biocompatible, biodegradable and other important properties. Sericin is widely used in biomedical applications, it is thought that sericin is a promising natural resource as an alternative medical material. This study analyzed pore diameter in sericin-bioplastic biocomposites by Taguchi method. Bioplastics of 3 variations of tapioca starch were 16 g, 14 g, and 10 g, mixed 80 ml of aquades and 6 ml of glycerin. Sericin was determined 0.03%, 0.1%, and 0.3% by weight of tapioca starch. The biocomposite undergoes freeze drying process and is frozen at -25oC, -45oC, and -80oC for one day. SEM test to see pore diameter and biocomposite structure. Optimal analysis was performed for optimal combinations of sericin-bioplastic biocomposites. The SEM results showed pore diameters qualified for regeneration of skin tissue on freezers C -C, F, and I -25oC biocomposites of 41.94 μm, 33.416 μm and 32.743 μm respectively. Calculation of average response and maximum SNR at 16 g tapioca starch, 0.03% sericin and -25oC temperature. The predicted and confidence interval values for averages are large from 11,656 μm and small from 54,602 μm, SNR is large from 31,940 μm and small from 33,642 μm. The optimal experimental conditions for confirmation of large pore diameter for averages were large from 32.342 μm and small from 34.206 μm, large SNR of 32.342 μm and small from 34.206 μm.

Keywords: Composition optimization, alternative medical materials, sericin- bioplastic biocomposites, Taguchi Methods, SEM